Wednesday, May 22, 2013

Team finds mechanism linking key inflammatory marker to cancer

Monday, May 20, 2013

In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.

Scientists call this Jekyll-and-Hyde molecule NF-kappa B. In healthy cells, it is a powerful "first responder," a vital part of the body's immune and inflammatory responses. It spends most of its life in the cell's cytoplasm, quietly awaiting orders. But when extracellular signals ? of a viral or bacterial invasion, for example ? set off chemical alarms, the cell unchains this warhorse, allowing it to go into the nucleus where it spurs a flurry of defensive activity, including the transcription of genes that trigger inflammation, promote cell proliferation and undermine cell death.

Researchers have known for years that a hyperactive form of NF-kappa B that gets into the nucleus and stays there is associated with various cancers. But they didn't know what was keeping it active in the nucleus.

"Normally in the cell NF-kappa B is in the cytosol, it's not in the nucleus, and it's not activated," said University of Illinois medical biochemistry professor Lin-Feng Chen, who led the new study. "You have to stimulate normal cells to see NF-kappa B in the nucleus. But in cancer cells without any stimulation you can see this nuclear form of NF-kappa B. The cell just won't die because of this. That is why NF-kappa B is so important in cancer."

In the new study, Chen's group found that another molecule known to help regulate gene expression, called BRD4, recognizes a specific amino acid on a subunit of the NF-kappa B protein complex after the amino acid has been marked with a specific tag, called an acetyl group. This "acetylation" allows the BRD4 to bind to NF-kappa B, activating it and preventing its degradation in cancer cells.

Previous studies had shown that BRD4's recognition of the acetylated subunit increased NF-kappa B activation, but this recognition had not been linked to cancer.

BRD4 belongs to a class of molecules that can recognize chemical markers on other proteins and interact with them to spur the marked proteins to perform new tasks. Chemical "readers" such as BRD4 are important players in the field of epigenetics, which focuses on how specific genes are regulated.

"In epigenetics, there are writers, there are readers and there are erasers," Chen said. The writers make modifications to proteins after they are formed, without changing the underlying sequence of the gene that codes for them. These modifications (such as acetylation) signal other molecules (the readers) to engage with the marked proteins in various ways, allowing the proteins to fulfill new roles in the life of the cell. Epigenetic erasers remove the marks when they are no longer of use.

Such protein modifications "have been shown to be critically involved in transcription regulation and cancer development," the researchers report.

To test whether BRD4 was contributing to the sustained presence of NF-kappa B in the nucleus of cancer cells, Chen and his colleagues exposed lung cancer cells in cell culture and in immune-deficient mice to JQ1, a drug that interferes with BRD4 activity. Exposure to JQ1 blocked the interaction of BRD4 and NF-kappa B, blocked the expression of genes regulated by NF-kappa B, reduced proliferation of lung cancer cells and suppressed the ability of lung cancer cells to induce tumors in immune-deficient mice, the researchers found.

The researchers also discovered that depletion of BRD4 or the treatment of cells with JQ1 induced the degradation of the NF-kappa B subunit recognized by BRD4.

Chen said that BRD4 likely prevents other molecules from recognizing the hyperactive NF-kappa B in the nucleus and marking it for degradation.

"This is an example of how epigenetic regulators and NF-kappa B may one day be targeted for the treatment of cancer," he said.

Researchers from Illinois biochemistry professor Satish Nair's laboratory and from the laboratory of James Bradner at the Dana-Farber Cancer Institute contributed to this study.

###

University of Illinois at Urbana-Champaign: http://www.uiuc.edu

Thanks to University of Illinois at Urbana-Champaign for this article.

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Source: http://www.labspaces.net/128313/Team_finds_mechanism_linking_key_inflammatory_marker_to_cancer

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Microsoft touts Xbox One as all-in-1 entertainment ? Artesia News

Kareem Choudhry, left, development manager for Microsoft Corp.'s Kinect motion-sensing device for the Xbox, demonstrates the level of detail in the camera of the new Kinect for the next-generation Xbox One entertainment and gaming console system to a visiting journalist, right, during a demonstration, Tuesday, May 21, 2013, in Redmond, Wash. (AP Photo/Ted S. Warren)

Kareem Choudhry, left, development manager for Microsoft Corp.?s Kinect motion-sensing device for the Xbox, demonstrates the level of detail in the camera of the new Kinect for the next-generation Xbox One entertainment and gaming console system to a visiting journalist, right, during a demonstration, Tuesday, May 21, 2013, in Redmond, Wash. (AP Photo/Ted S. Warren)

REDMOND, Wash. (AP) ? Microsoft thinks it has the one.

The company unveiled the Xbox One, an entertainment console that wants to be the one system households will need for games, television, movies, sports and other entertainment. It will go on sale later this year, for an undisclosed price.

For the past two years, Microsoft?s Xbox 360 has outsold its rivals. But it?s been eight years since that machine came out, and Microsoft is the last of the three major console makers to unveil a new system. In those eight years, Apple launched the iPhone and the iPad, ?FarmVille? rose and fell and tablets began to threaten desktop computers, changing how people interact with games and beyond.

Now, the stakes are high as Microsoft, Sony and Nintendo are all using their latest machines not only to draw gamers but also to command the living room. The goal is to extend their reach beyond loyal legions of hardcore gamers and to become as important to our lives at home as smartphones have become to our lives on the go.

Don Mattrick, Microsoft?s president of interactive entertainment business, said the company has spent the past four years working on an ?all-in-one home entertainment system.?

At an hour-long unveiling at the company?s Redmond, Wash., headquarters on Tuesday, Microsoft executives used voice controls to switch back and forth seamlessly between watching live TV, listening to music, playing a movie and browsing the Internet ? all while running apps for stuff like fantasy football and Skype chats on the side of the screen.

?It really extends the home entertainment experience,? Gartner analyst Brian Blau said.

He said the console seems to appeal to ?more than just a core gamer in the family? and should be of interest to all types of audiences, from sports players to TV viewers to those who are ?social and want to share things.?

The Xbox One unveiling follows Nintendo Co.?s launch of the Wii U in November and Sony Corp.?s tease in February of the upcoming PlayStation 4. Each of the new consoles has shifted away from simply serving as gaming machines, as they incorporate streaming media apps and social networking features.

People will be able to connect their cable or satellite set-top box and watch TV through the Xbox One. It will have its own channel guide and allow viewers to change channels by voice command.

Senior Vice President Yusuf Mehdi demonstrated how the console switched quickly between channels after saying show names such as ?Mary and Martha? or commands like ?watch MTV.? His voice command of ?What?s on HBO?? brought up the channel guide for HBO.

?No more memorizing channels or hunting for the remote control,? Mehdi said.

The interface for the TV goes well beyond the functionality in the Wii U, which still requires users to press buttons to change the input source on the TV. Xbox One seamlessly flipped between games, movies and TV shows with voice commands.

In addition to the console, Microsoft unveiled a new version of its camera-based Kinect system with better motion and voice detection, including the ability to recognize faces, tell if you?re smiling or talking and gauge your heart rate. In a demonstration, the new sensor detected up to seven people in front of it. Microsoft said the new Kinect will be included with the Xbox One and is deeply integrated into the system, but it won?t necessarily always be watching users in their living rooms.

?There?s the ability for you to manage the privacy settings so you can turn it off,? Marc Whitten, Microsoft?s chief product officer of interactive entertainment business, said in an interview in his office after Tuesday?s presentation. ?Just like the 360, the biggest thing for us is that you are in control of your privacy.?

The company also introduced a more ergonomic Xbox controller, with a slightly different layout from the Xbox 360 controller and trigger buttons that vibrate. The new console will also add the ability to play Blu-ray discs, matching what Sony has in its older PlayStation 3.

The Xbox One won?t require a constant connection to the Internet, but having it will be useful for many of the gaming and entertainment features. The Xbox has been popular largely because of its Xbox Live service, which lets users play games online with other players with annual plans that cost as much as $60 a year.

?The box wants to connect to the Internet,? Whitten said. ?That said, we understand the Internet is flakey. It doesn?t always work. We want to make sure you can still play your games, watch movies and watch TV if the Internet is down.?

Despite talk that Microsoft might restrict the use of games previously owned by others, the company confirmed that the Xbox One will indeed play used games, but it didn?t provide details on how that would work. It said games for the Xbox 360 won?t work on the new system because the underlying technology is different, though the company said it will continue to make games for the older machine. Whitten said the Xbox 360 ?is going to be incredibly vibrant for some time to come.?

Among the games previewed for Xbox One were the military shooter ?Call of Duty: Ghosts? from Activision Blizzard Inc., soccer extravaganza ?FIFA 14? from Electronic Arts Inc. and racing simulator ?Forza Motorsport 5? and time bender ?Quantum Break,? both from Microsoft Game Studios. Microsoft said more games will be shown at next month?s E3 video game conference in Los Angeles.

The company said there will be more than 15 games available exclusively on the Xbox One in its first year, eight of them new franchises. In recent years, the Xbox has been the exclusive home to such popular gaming franchises as sci-fi shooter ?Halo? and alien shoot-?em-up ?Gears of War.?

Wedbush analyst Michael Pachter said Tuesday?s presentation was more general than what Microsoft will likely give at E3, where games will be central as thousands of game industry insiders, bloggers and journalists gather for the annual industry conference.

?They didn?t focus on games,? he said. ?They focused on everything else.?

That everything else includes a multiyear agreement between Microsoft and the National Football League to develop new interactive viewing experiences for pro football games through such products as the Xbox One and Microsoft?s Surface tablet computer. Fans will be able to watch games, chat with other fans, view statistics, access highlights in real time and gather fantasy information about players and teams ? all on a single screen. For those who prefer multiple screens, fans can get an even deeper experience on mobile devices such as tablets.

Microsoft is also branching into creating original content beyond games, following the trend of other technology companies such as Amazon.com Inc. and Netflix Inc. Director Steven Spielberg will produce a TV series based on the ?Halo? games.

The original Xbox debuted in 2001, and its high-definition successor premiered in 2005. The Xbox represents a small fraction of Microsoft?s overall revenue, but it is an important consumer-facing business for Microsoft and offers a way to direct traffic to other Microsoft-owned services, including Skype. Microsoft?s stock fell 23 cents, or less than 1 percent, to close Tuesday at $34.85.

Nintendo kicked off the next generation of gaming in November with the launch of the Wii U, the successor to the popular Wii system. The Wii U features an innovative tablet-like controller, though its graphics is on par with the previous-generation Xbox 360 and Sony?s PlayStation 3. Nintendo said the console sold just 3.45 million units by the end of March, well below expectations.

Sony was next, teasing plans for its upcoming PlayStation 4 ? without showing the actual box ? at a February event in New York. The reaction to that console, which featured richer graphics and more social features, was mixed. The PS4 is expected by the holidays.

Microsoft didn?t waste any time showing off the Xbox One console, new Kinect sensor and Xbox controller at the beginning of Tuesday?s presentation.

___

Barbara Ortutay reported from New York. AP Business Writer Ryan Nakashima in Los Angeles and AP Pro Football Writer Barry Wilner in Boston contributed to this story.

___

Online:

http://www.xbox.com

___

Follow AP Entertainment Writer Derrik J. Lang on Twitter at http://www.twitter.com/derrikjlang

This entry was posted on May 21, 2013, 5:22 pm and is filed under Entertainment. You can follow any responses to this entry through RSS 2.0. Both comments and pings are currently closed.

Source: http://www.artesianews.com/2013/05/21/ap-news/entertainment-ap-news/microsoft-touts-xbox-one-as-all-in-1-entertainment/

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Tuesday, May 21, 2013

How to Give Ugly Landfills a Second Life

The Daily Beast on the second life of landfills?Miranda Green observes a new trend among communities hoping to conceal unsightly landfills and garbage dumps: covering the sites with solar panels. "Many states and cities have long been turning trash into treasure by burning garbage to create heat and electricity, or by harvesting the methane gas that is released as junk decomposes," Green writes. "But in a new twist on this theme, several cities and municipalities are transforming capped landfills?the ultimate waste of space?into solar-power plants. ... Benefits come in the form of renewable electricity. Instead of letting landfills sit for years as the land settles and compacts, towns can place solar panels on the wide-open space and continue to make money from the energy collected."

RELATED: The Future of Oil; Canada's Keystone Power Play

Ars Technica on??climigration??John Timmer discusses a recent paper that takes note of a phenomenon called "climigration" ? where communities and even entire towns threatened by climate change decide to uproot and move to a less volatile area. "As climate change and sea level rise are permanently altering the landscape, it may not make sense to rebuild in precisely the same location," he writes. "That reality has already arrived for many communities in northern Alaska, where the vanishing sea ice and permafrost have left entire towns at risk of being washed away. If the experience of those residents is anything to go by, we're woefully unprepared for the new reality."

RELATED: Is Energy Independence a Myth?

The Washington Post on the left's reaction to Obama's energy deliberations "If you want to get a sense of how impatient some of President Obama?s most loyal supporters are getting when it comes to climate change," begins Juliet Eilperin,?"consider this: They?re planning to conduct protests at meetings of the grassroots advocacy organization run by his former top campaign aides." Eilperin explains the dilemma facing activists trying to influence the President: "Obama may very well address environmentalists? concerns this year by rejecting TransCanada?s application to build the Keystone across the U.S.-Canada border, and by regulating greenhouse gas emissions from existing power plants. But the longer he takes to act, the more likely his primary organizing group will face an organized rebellion of its own."

RELATED: How Electric Cars Make Money; Fear of a Carbon Trading Planet

Reuters on how fracking caused a battle over water?Ernest Scheyder begins with a saying common in the parts of North Dakota affected by a recent oil boom: "In towns across North Dakota, the wellhead of the North American energy boom, the locals have taken to quoting the adage: 'Whiskey is for drinking, and water is for fighting.'" The maxim hints at what is in fact an ongoing battle to secure usable water in the area. "It's not that they lack water, like Texas and California," the author says. "They are swimming in it, and it is free for the taking. Yet as the state's Bakken shale fields have grown, so has the fight over who has the right to tap into the multimillion-dollar market to supply water to the energy sector."

RELATED: North Carolina Wants to Ban Tesla Cars

The New Yorker?on the Keystone XL pipeline's impact?What does the decision about the Keystone XL pipeline boil down to? In the midst of a heavy lobbying campaign in Washington, D.C., Elizabeth Kolbert weighs the principle arguments driving the debate. First, the pro side: "The arguments in favor of Keystone run more or less like this: Americans use a lot of oil?more than eighteen million barrels per day. It has to come from somewhere, and Canada is a more reliable trading partner than, say, Iraq." And the con: "?If we take the future at all seriously, which is to say as a time period that someone is going to have to live in, then we need to leave a big percentage of the planet?s coal and oil and natural gas in the ground."

Source: http://news.yahoo.com/ugly-landfills-second-life-231655229.html

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Monday, May 20, 2013

Obama to speak on legality of drone program (The Arizona Republic)

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Comet ISON: How to See Potential 'Comet of the Century' Online Today

The much-anticipated incoming Comet ISON, which some scientists hope will become the "comet of the century" later this year, may not be visible to the naked eye yet, but you don't have to wait months to see this icy wanderer. The comet takes center stage in an online telescope webcast today (May 19).

Comet ISON was first discovered last year and is currently expected to swing extremely close by the sun in late November, when it will be at its best and brightest of the year. In anticipation of the comet's arrival, the online Slooh Space Camera will offer live telescope views of the object beginning at 4:45 p.m. EDT (2045 GMT).

You can watch the Comet ISON webcast live on SPACE.com, courtesy of Slooh Space Camera. [See the more amazing photos of Comet ISON]

Today's webcast marks Slooh's fourth monthly webcast dedicated to tracking Comet ISON's progress through the solar system. During today's 30-minute live show, Slooh officials will provide views of Comet ISON from the firm's remotely operated telescopes in the Canary Islands, off the west coast of Africa.

Senior space scientist Padma Yanamandra-Fisher of the Space Science Institute in Boulder, Colo., will join Slooh producer Paul Cox in the comet webcast. Yanamandra-Fisher is helping coordinate NASA's Comet ISON Observing Campaign to track the comet. The international campaign is bringing together scientists around the world to plan out observations of ISON.

NASA has already used several spacecraft, including sun-watching Stereo probes and the Hubble Space Telescope, to observe ISON. An unmanned balloon mission is also among the expeditions planned to observe ISON.

Comet ISON has drawn worldwide attention from stargazers and scientists, including NASA, because of its close approach to the sun on Nov. 28, when it will be just 730,000 miles (1.2 million kilometers) from the sun. During that close encounter with the sun, Comet ISON could become one of the brightest comets in decades. However, the comet could also fizzle out.

Comet ISON was discovered in September 2012 by Russian amateur astronomers Artyom Novichonok and Vitali Nevski using the International Scientific Optical Network (ISON) of remotely operated telescopes. The comet is officially known by the identification C/2012 S1 (ISON).

On April 10, scientists used the Hubble Space Telescope to observe Comet ISON. At the time it was about 386 million miles (621 million kilometers) from the sun and 394 million miles (634 million kilometers) from Earth.

When observed by Hubble, the comet's nucleus was about 3 miles (5 km) across and a dusty tail that stretches more than 57,000 miles (92,000 km) long.

Editor's note:?If you have an amazing picture of Comet ISON or any other night sky view that you'd like to share for a possible story or image gallery, send photos, comments and your name and location to managing editor Tariq Malik at?spacephotos@space.com.

To follow the Slooh webcast directly using Slooh's iPad app or the Slooh website, visit: http://www.slooh.com.

Email Tariq Malik at tmalik@space.com or follow him @tariqjmalikand Google+. Follow us @Spacedotcom, Facebookand Google+. Original article on SPACE.com.

Copyright 2013 SPACE.com, a TechMediaNetwork company. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://news.yahoo.com/comet-ison-see-potential-comet-century-online-today-151324702.html

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Rosie Pope helps navigate exotic baby gear

NEW YORK (AP) ? Amid the purveyors of belly casts and placenta pills, sonogram art and cord banks at a recent baby gear extravaganza stood a smiling Rosie Pope, pregnancy advice guru, mommy concierge to the rich and, with any luck, the Martha Stewart of maternity.

"There's Rachael Ray for cooking and Rachel Zoe for style, but who in motherhood? That's my dream," said the affable mom of three as she signed copies of her pregnancy guide, "Mommy IQ," showed off her maternity clothing line and chatted up fans Saturday at the New York Baby Show.

Making sense of maternity and baby gear these days isn't easy, so Pope may just get her shot. More than a few moms-to-be were befuddled as they walked the crowded show floor, some with exhausted husbands in tow, at a cavernous pier just off the West Side Highway.

There's the "Tortle," for example. It's an infant hat with a soft wedge built in to battle flat head syndrome. And there's Clean Bee Baby, an eco-friendly cleaning service for strollers and car seats.

The sellers of the Woolino were there. It's a four-season wearable sleep bag for baby in Australian merino wool that promises to regulate body temperature, wick away moisture and last until age 2 in place of those dangerous things called blankets.

There were also numerous reinventions of the wearable baby carrier, bright and cheery seats and rides of all kinds, including one that looks like an actual car, and all-natural everything, from squeezable baby fruit to Kinder by Nature herbal wipes, loaded with certified organic aloe vera, tea tree and ylang ylang extracts.

A couple of doulas turned up with a pink Mini Cooper, extolling such services as "placenta encapsulation." It involves dehydrating one's placenta, turning it into a powder and putting it inside capsules for ingestion as a postpartum supplement. Which is not to be confused with a reinvention of prenatal vitamins as a powder you can sprinkle on food or mix with a liquid, or with services that will store umbilical cord blood for its stem cells soon after birth.

In addition to a little trend-spotting (highlighter orange is in and the nursery animal of the moment is the hedgehog), Pope offered her view on the explosion of gear for mom, dad and baby.

"There's so much we do not need," she said. "What we do need is a safe place for the baby to sleep. We do need a safe car seat. We do need a stroller system that the car seat can snap into. What we do need is SOME clothes. What we don't need is shoes and hair accessories and wipe warmers and bottle warmers and all of this sort of extra stuff that really is just adding complication to what you're doing rather than making your life easier."

Like gear, maternity clothes have come a long way, as have some famous expectant moms, she said.

Of the very pregnant Kim Kardashian's criticized floral Met Gala gown by Riccardo Tisci for Givenchy, Pope offers:

"I think that maybe she's a PR genius since that caused her a lot of attention, but really what I always tell my clients is stay true to your sense of style. Kim was very sensuous and her clothing was generally very tight and you could see her curves. But an upholstered turtleneck gown with matching gloves is really hard for anybody to pull off. She is a beautiful pregnant woman, though."

And the other high-profile mom-to-be, the former Kate Middleton?

"She is keeping to her sense of style, so very understated, very demure and classic and tailored. And what she's really showing, which I love, is that you don't have to just wear stretchy clothes when you're pregnant."

In addition to sellers of wearable baby carriers and a foundation looking for donations to fund kiddie yoga lessons for the underprivileged, the makers of modesty covers for nursing women were on hand at the show sponsored by New York Family magazine.

Pope said she used one called the Hooter Hider but made clear she casts no judgments on breast-feeding versus bottle feeding. She nursed her first, now 4, for about six months but said "it didn't work" for her second. When her third came along she decided as a busy working mom on a combination of pumping and formula.

"There's a lot of pressure to breast-feed and I think if you can do it, it's a wonderful thing, but it doesn't work for everybody," Pope said.

The star of Bravo's "Pregnant in Heels" reality series takes a similar approach to many maternity issues in her book, out last October with medical-related advice by one of New York City's foremost obstetrician-gynecologists, Amos Grunebaum, who was Pope's doctor as she navigated infertility treatment.

"So many of the books I find to be quite heavy and quite hard to figure out whether they're saying yes or no. It's always in the middle, the advice. I wanted to know what is right and what is wrong and then what is up to me. That's really important."

She professes zero tolerance for caffeine and alcohol during pregnancy, "but then I am much more open-minded when it comes to breast-feeding and when it comes to attachment parenting or sleeping. I really believe every family is very, very different and what's right for one person is not right for another."

In decades past, maternity advice was "this way or the highway," but so many options and so much readily available information today is a "blessing and a curse," Pope acknowledged. "If you can navigate your way through that you can really find a path that is wonderful for you."

Agnieszka Golasik of Brooklyn, an artist by way of Poland, wasn't looking to help expectant moms navigate so much as decorate. She'll turn your sonogram pregnancy image into a psychedelic portrait of your fetus through her company Your Baby to Be, at a starting price of $250.

"I was experimenting with these images for a series of small monotypes when I found out I was pregnant," Golasik said at the booth she shared with co-founder Margaret Blat. "This is a special time and new way to remember your baby."

The folks over at Cast in Time were of similar minds. They'll take a plaster cast of your naked and pregnant silhouette, from pubic bone to breasts, decorate it and frame it for hanging, at a minimum of $495.

Said the founder, who goes by Bindia: "Pregnant women are beautiful."

___

Follow Leanne Italie on Twitter at http://twitter.com/litalie

Source: http://news.yahoo.com/rosie-pope-helps-navigate-exotic-baby-gear-193829282.html

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Sunday, May 19, 2013

A look at why the Benghazi issue keeps coming back

FILE ? In this Jan.23, 2013, file photo U.S. Secretary of State Hillary Rodham pounds her fist as she testifies on Capitol Hill in Washington at the Senate Foreign Relations Committee hearing on the deadly September attack on the U.S. diplomatic mission in Benghazi, Libya, that killed Ambassador Chris Stevens and three other Americans. Republicans and Democrats began condemning each other's response to Benghazi within hours of the first shots fired. The issue has flared and dimmed ever since, revived by new testimony, reports or documents like newly released emails. (AP Photo/Pablo Martinez Monsivais, File)

FILE ? In this Jan.23, 2013, file photo U.S. Secretary of State Hillary Rodham pounds her fist as she testifies on Capitol Hill in Washington at the Senate Foreign Relations Committee hearing on the deadly September attack on the U.S. diplomatic mission in Benghazi, Libya, that killed Ambassador Chris Stevens and three other Americans. Republicans and Democrats began condemning each other's response to Benghazi within hours of the first shots fired. The issue has flared and dimmed ever since, revived by new testimony, reports or documents like newly released emails. (AP Photo/Pablo Martinez Monsivais, File)

House Oversight Committee Chairman Darrell Issa, R-Calif., left, welcomes Gregory Hicks, former deputy chief of mission in Libya, number two in rank to slain U.S. Ambassador Christopher Stevens, as he arrives to testify about last year's deadly assault on the U.S. diplomatic mission in Benghazi, Libya, on Capitol Hill in Washington, Wednesday, May 8, 2013. At right is Eric Nordstrom, the State Department's former regional security officer in Libya. House Republicans, led by Issa, insist the Obama administration is covering up information about the attack, rejecting administration assurances to the contrary and stoking a controversy with implications for the 2016 presidential race. (AP Photo/J. Scott Applewhite)

FILE ? In this Nov. 27, 2012, file photo Senate Armed Services Committee members, Sen. Lindsey Graham, R-S.C., foreground, and Sen. Kelly Ayotte, R-N.H., speak to reporters on Capitol Hill in Washington after meeting with UN Ambassador Susan Rice to discuss statements she made about the attack on the U.S. Consulate in Libya that killed four Americans. Republicans and Democrats began condemning each other's response to Benghazi within hours of the first shots fired. The issue has flared and dimmed ever since, revived by new testimony, reports or documents like newly released emails. (AP Photo/Susan Walsh, File)

(AP) ? The night of smoke, chaos, gunfire and grenades that killed four Americans in Benghazi, Libya, is well-documented. Eight months later, it is the decisions made back in Washington that remain murky and in perpetual dispute.

Why was a diplomatic outpost left so poorly protected? Should the Pentagon have rushed jets or special forces to the rescue when the assault began? Did President Barack Obama's administration obscure the true nature of the terrorist attack to help him get re-elected?

Congressional Republicans are poking for evidence of incompetence and cover-up in the ashes of the Sept. 11 anniversary attack. Obama dismisses their probes as a politically driven "sideshow."

The release this past week of 100 pages of government emails and notes is the latest fodder, as numerous Benghazi investigations continue.

A look at the issue:

___

WHY NOW?

Republicans and Democrats began condemning each other's response to Benghazi within hours of the first shots fired. The issue has flared and dimmed ever since, revived by new testimony, reports or documents like the newly released emails.

Republican lawmakers say they won't stop until they get their questions answered.

Democrats accuse the GOP of flogging the issue for partisan gain.

The focus on Benghazi and other controversies makes it harder for Obama to press his second-term agenda. Emphasizing the State Department's failings during her tenure could be especially damaging to former Secretary of State Hillary Rodham Clinton, the early favorite among Democrats who might seek the presidency in 2016.

Sen. Rand Paul of Kentucky, a possible Republican presidential candidate, already is arguing that the attack "precludes Hillary Clinton from ever holding office."

The controversy also helps Republicans raise money and fire up their conservative base heading into next year's congressional elections.

___

SEPT. 11, 2012

The night of the attack, as described by the State Department's review board and other accounts:

Seven Americans are at State's temporary residential compound in Benghazi that night: U.S. Ambassador Chris Stevens, visiting from the embassy in Tripoli; computer specialist Sean Smith and five diplomatic security officers. They are a minority among U.S. personnel in Benghazi; most work for the CIA, which operates a secret "annex" about a mile away.

Egyptian demonstrators had scaled the walls of the U.S. Embassy in Cairo hours earlier to protest an American amateur filmmaker's video mocking the Prophet Muhammad. But there were no demonstrations that day in Benghazi. The attack begins suddenly around 9:40 p.m. ? gunfire, explosions, sounds of chanting and then dozens of armed men swarming through the compound's main entrance. Libyans hired to guard the compound flee.

A security officer hustles Stevens and Smith into a fortified "safe room." It fills with blinding smoke when the attackers set the building on fire with diesel fuel, and the two men become separated from the security officer.

A CIA team from the annex arrives about 25 minutes into the attack and helps search for the two diplomats inside the smoke-filled room, while gunfire continues outside. Only Smith's body is found. Eventually the U.S. personnel escape in armored vehicles, plowing through gunfire and grenade blasts to the CIA annex across town. Rocket-propelled grenades and mortar fire target the annex intermittently for an hour after midnight.

A team of six security officials summoned from Tripoli arrives around 5 a.m. Soon after, another assault on the annex begins. A mortar blast kills CIA security contractors Tyrone Woods and Glen Doherty. About an hour later, a Libyan military unit arrives to help evacuate the U.S. personnel.

After the Americans fled the diplomatic compound, Benghazi civilians found Ambassador Stevens in the wreckage and drove him to a hospital, but he couldn't be saved. Like Smith, he died of smoke inhalation.

___

POLITICAL FROM THE FIRST

The calamity in Benghazi was the kind of autumn surprise that can rock a presidential race.

The night of Sept. 11, before word of Stevens' death was out, Republican nominee Mitt Romney issued a hurried statement about violence in Egypt and Libya, criticizing the State Department as too sympathetic to Muslim protesters. Critics, even some in his own party, faulted Romney for politicizing a crisis before the facts were in.

A month later in a combative presidential debate, Romney took another tack. He jumped on Obama for being too slow to acknowledge that terrorism was committed on his watch.

"It took the president 14 days before he called the attack in Benghazi an act of terror," Romney insisted.

"Get the transcript," Obama snapped back, referring to his remarks the day after the assault.

In that Rose Garden appearance and similar words the next day, Obama had said that "acts of terror" would not shake U.S. resolve. He also condemned the violent protests that were sweeping through Muslim nations, sparked by anger over the Muhammad video.

In interviews over the next two weeks, Obama blamed the attack on extremists but steered clear of using any form of the word "terror." Other administration officials did the same and continued to conflate the Benghazi attack with the protests elsewhere.

Finally, at a Sept. 20 news briefing, White House spokesman Jay Carney said it was "self-evident that what happened in Benghazi was a terrorist attack."

___

THE TALKING POINTS

The question of the moment: Were the "talking points" drawn up within days of the attack deliberately misleading?

The document, outlining the government's public message, was sent to members of Congress and to Susan Rice, the U.S. ambassador to the United Nations, who made the round of Sunday morning talk shows five days after the attack.

Republicans accuse Rice of deceiving the American people. They say that, working from the talking points, she passed off an attack by heavily armed terrorists possibly linked to al-Qaida as something less damaging to Obama's terror-fighting credentials.

Rice described the attack as a "horrific incident where some mob was hijacked, ultimately, by a handful of extremists."

The White House says Rice reflected the best information available while facts were still being gathered. Republican critics say the administration should have known by then that there was no mob of protesters and the attack was a premeditated act of terrorism.

Two months after her TV interviews, the controversy ended Rice's chance of following Clinton as secretary of state.

___

STILL TALKING

Those talking points from September are in the news now because of new revelations about how they were crafted.

Republicans demanded to see emails exchanged by administration officials who revised and edited the talking points. On Wednesday, the White House publicly released 100 pages of emails and notes, saying congressional Republicans had misrepresented what they say.

Most of the email back-and-forth is between the State Department and the CIA, the entities whose facilities were attacked in Benghazi. White House and FBI officials were also in the discussions.

From the first draft, the CIA described the attack in Benghazi as a spontaneous outgrowth of the movie protests that began in Egypt ? which indicates that was the theory in Washington then. However, the No. 2 diplomatic official in Libya at the time says he knew immediately it wasn't true and was demoted after he questioned the version of events Rice recited on TV.

One edit especially has been criticized as political: Victoria Nuland, then State's spokeswoman, sought removal of a reference to a CIA warning about the potential for anti-American demonstrations in Cairo and jihadists trying to break into that embassy. Nuland wrote that "could be abused" by lawmakers to criticize her department for failing to take heed.

Also deleted were references to the CIA's past warnings about dangerous extremists linked to al-Qaida in Benghazi.

After many deletions, the meat of the talking points read: "The currently available information suggests that the demonstrations in Benghazi were spontaneously inspired by the protests at the U.S. Embassy in Cairo and evolved into a direct assault against the U.S. diplomatic post in Benghazi and subsequently its annex. There are indications that extremists participated in the violent demonstrations."

___

UNPROTECTED

The month after Obama was re-elected, an independent review board issued its harsh verdict.

Senior officials in Washington had failed to protect the Benghazi mission, even after diplomats in Libya asked for more security, said the panel appointed by the State Department.

Since the overthrow of dictator Moammar Gadhafi, eastern Libya has been plagued by violence and awash with heavily armed militias. The U.S. compound as well as British diplomats and the Red Cross had been targeted by explosives in smaller attacks several times over the spring and summer.

The danger was obvious.

And yet security was "inadequate for Benghazi and grossly inadequate to deal with the attack that took place," the Accountability Review Board concluded.

Four State Department officials were reassigned or resigned as a result.

"We clearly fell down on the job with regard to Benghazi," Deputy Secretary of State William Burns told lawmakers.

Republicans put the focus on Clinton's responsibility. In combative congressional hearings in January, the outgoing secretary of state said the cables from Benghazi seeking help never reached her.

"I did not see these requests. They did not come to me," she said. "I did not approve them. I did not deny them."

Obama called the poor security "a huge problem" and said changes would be made to protect risky posts.

Democrats tried to shift some blame to congressional Republicans, complaining that they cut $300 million from the Obama administration's budget request of $2.6 billion for diplomatic and embassy security in 2012.

___

WHERE WAS THE CAVALRY?

Could the military have done more to help on Sept. 11? A former top diplomat thinks so.

Gregory Hicks, who was Stevens' No. 2 and monitoring the crisis from Tripoli that night, suggests that sending fighter jets or even a cargo plane overhead might have scared off the insurgents with a show of force. That might have saved the lives of the two CIA contractors by preventing the final assault on the CIA annex, which came about eight hours after the first attack on the diplomatic mission, Hicks told a House committee.

Hicks also said four members of a special forces team in Tripoli wanted to fly on a Libyan plane to Benghazi but were told to stand down. Pentagon officials said the evacuation was already beginning by then and those forces would have arrived too late.

Gen. Martin Dempsey, chairman of the Joint Chiefs of Staff, told the Senate there wasn't enough information about what was happening on the ground to send in aircraft. For example, for several hours officials didn't know what had happened to the ambassador.

Former Defense Secretary Leon Panetta made the same point. "You can't just willy-nilly send F-16s there and blow the hell out of a place without knowing what's taking place," Panetta told senators.

State's review board concluded the military did what it could. An unarmed Predator drone flew over the diplomatic post beginning shortly after 11 p.m. to gather information. Two military personnel were with the team from Tripoli that arrived at the CIA annex in the morning. A C-17 from Germany carried the evacuated Americans out of Tripoli. Special operations forces and other personnel who were deployed from Europe and the United States in response to the crisis didn't reach Libya in time to help.

"The interagency response was timely and appropriate," according to the review board, "but there simply was not enough time given the speed of the attacks for armed U.S. military assets to have made a difference."

___

WHAT'S NEXT

The FBI is still investigating who carried out the attack, and Attorney General Eric Holder says there has been "very, very substantial progress."

Republicans on five House committees are pursuing inquiries. Many GOP lawmakers are pushing House Speaker John Boehner, R-Ohio, to appoint a special select committee to investigate.

The leaders of the review board, veteran diplomat Thomas Pickering and former Joint Chiefs Chairman Mike Mullen, have offered to testify publicly about their findings and to answer critics who say the probe was incomplete. Rep. Darrell Issa, R-Calif., chairman of the House Oversight committee, has issued a subpoena to compel Pickering to testify in closed session first.

And congressional Republicans say they will keep pressing for more documents, such as details of military orders during the attack.

___

Associated Press writer Donna Cassata contributed to this report.

___

Follow Connie Cass on Twitter: http://www.twitter.com/ConnieCass

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-05-18-US-Benghazi-News-Guide/id-86a681a778e342bd973ae4656c308c9d

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Cannes helps actors Bejo and Rahim cross borders

CANNES, France (AP) ? The magic and glamour of Cannes can be hard to spot on a day when rain is lashing the palm trees, roiling the gray Mediterranean and pooling in puddles along the Croisette.

But the world's leading film festival can transform careers ? something no one knows that better than actors Berenice Bejo and Tahar Rahim, stars of director Asghar Farhadi's festival entry "The Past."

Bejo shimmered on-screen in Cannes two years ago in "The Artist," her director husband Michel Hazanavicius' vivacious silent homage to Hollywood's Golden Age. It went on to win five Academy Awards, including best picture.

Rahim was the breakout star of the 2009 festival in Jacques Audiard's poetic and brutal prison drama "A Prophet," as a youth growing to manhood behind bars.

Cannes exposure helped boost both performers onto the international stage. While once most European actors could choose between stay at home and playing Hollywood villains, their paths suggest a more globalized movie world.

"It was quite a miracle for me," Bejo said Saturday, as rain drummed remorselessly on a Cannes rooftop lounge. "Two years ago my life changed a little bit in Cannes.

"I don't think Asghar Farhadi would have cast me in this movie if I hadn't done 'The Artist.'"

It's hard to think of two movie styles further apart than the flamboyant artifice of "The Artist" and the anatomically detailed domestic drama of "The Past"

Bejo plays Marie, a harried Frenchwoman with two children, a new boyfriend with a young son, and an Iranian ex who has returned after four years to finalize their divorce. Rahim is her boyfriend Samir, a man with complex family ties of his own.

All the characters are trying to move on ? but the past keeps dragging them back.

Bejo said she did a screen test for Farhadi, then didn't hear from him for a month, so initially thought she hadn't got the part.

"He said to me, I was looking into your face if I could see the doubt," she said. "I guess because he saw me in movies where I was quite positive, quite sunny, quite glamorous. He needed to see if I could show another part of myself ? and I guess he found it."

For Bejo, as for Rahim, working with the Iran director was a dream come true. "The Past" is the first film Farhadi has shot outside his homeland, and the actors say they loved his working methods ? two months of rehearsal to delve into character, break down barriers and forge bonds, followed by a four-month shoot.

With its Iranian director and largely French cast, it's one of several border-hopping movies at Cannes this year. French director Arnaud Desplechin's made-in-America "Jimmy P.: Psychotherapy of a Plains Indian" stars France's Mathieu Amalric and Puerto Rican actor Benicio Del Toro. Another French filmmaker, Guillaume Canet, has a multinational cast including Clive Owen, Billy Crudup and Marion Cotillard in his New York crime drama "Blood Ties."

It's a trend Bejo is happy to embrace.

"In America you have Christoph Waltz, you have Marion Cotillard," she said. "In France we have Italian and Spanish actors. ... I think it's great. We are used to strangers and foreign accents, and it's great that we can see that in our movies now."

Both she and Rahim have been busy since their Cannes breakthroughs. Bejo recently made French heist movie "The Last Diamond" and soon starts filming Hazanavicius' next project, a war movie set in Chechnya.

Rahim's projects include the English-language Roman-era adventure "The Eagle" and another movie appearing at Cannes this year, the nuclear power plant romance "Grand Central."

Coming up, he plays a cop in the French movie "The Informant," and is currently shooting a globe-spanning 1920s-set drama with Turkish-German director Fatih Akin, another pillar of culture-crossing cinema.

Despite the busy international career ? and post-"Prophet" expressions of interest from the United States ? Rahim says Hollywood remains a hard nut to crack for non-Anglophone actors.

"It's not what you expect at first," Rahim said. "You'd like to be with Michael Mann or (directors) like this, but you don't have those parts that easily. Because first you have to speak English, you have to erase your accent."

For now, he's just happy to be back in Cannes, an experience that is easier the second time around.

"The difference is that now I'm not afraid when I come here," he said. "I'm (saying) 'OK I'm going to take every good vibe and keep it.'"

___

Jill Lawless can be reached at http://Twitter.com/JillLawless

Source: http://news.yahoo.com/cannes-helps-actors-bejo-rahim-cross-borders-165726670.html

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Teen's invention could charge your phone in 20 seconds

innovation

14 hours ago

Image of Eesha Khare

Intel

Eesha Khare, 18, of Saratoga, Calif., received the Intel Foundation Young Scientist Award of $50,000 for the invention of a tiny energy-storage device.

Waiting hours for a cellphone to charge may become a thing of the past, thanks to an 18-year-old high-school student's invention. She won a $50,000 prize Friday at an international science fair for creating an energy storage device that can be fully juiced in 20 to 30 seconds.

The fast-charging device is a so-called supercapacitor, a gizmo that can pack a lot of energy into a tiny space, charges quickly and holds its charge for a long time.

What's more, it can last for 10,000 charge-recharge cycles, compared with 1,000 cycles for conventional rechargeable batteries, according to Eesha Khare of Saratoga, Calif.

"My cellphone battery always dies," she told NBC News when asked what inspired her to work on the energy-storage technology. Supercapacitors also allowed her to focus on her interest in nanochemistry ? "really working at the nanoscale to make significant advances in many different fields."

To date, she has used the supercapacitor to power a light-emitting diode, or LED. The invention's future is even brighter. She sees it fitting inside cellphones and the other portable electronic devices that are proliferating in today's world, freeing people and their gadgets for a longer time from reliance on electrical outlets.

"It is also flexible, so it can be used in rollup displays and clothing and fabric," Khare added. "It has a lot of different applications and advantages over batteries in that sense."

Khare's invention won her the Intel Foundation Young Scientist Award at the Intel International Science and Engineering Fair, conducted this week in Phoenix, Ariz. For more information about the event and other prize winners, check out our earlier coverage.

John Roach is a contributing writer for NBC News. To learn more about him, visit his website.

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Saturday, May 18, 2013

Google Now Introduces Mark Up Tools For Select Partners To Flag Flights, Hotel Stays And Reservations In Emails

google-now-stuffGoogle made a relatively quiet announcement today regarding how it's pushing the developer ecosystem forward around Google Now, its intelligent personal assistant for Android devices. The company has begun extending mark up tools for emails from select partners, which help highlight flight schedules, hotel bookings and various types of reservations, to make sure that Gmail can spot that information and use it to auto-generate helpful reminders in Google Now.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/TlTpS4qYDV0/

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Record Powerball jackpot inspires office pools

Sheila Sutton updates the Powerball prize money sign at the Super C convenience store in Lincoln, Neb., Friday, May 17, 2013. Powerball officials say the jackpot has climbed to an estimated $600 million, making it the largest prize in the game's history and the world's second largest lottery prize. Sutton sold a million dollar powerball ticket on Tuesday. (AP Photo/Nati Harnik)

Sheila Sutton updates the Powerball prize money sign at the Super C convenience store in Lincoln, Neb., Friday, May 17, 2013. Powerball officials say the jackpot has climbed to an estimated $600 million, making it the largest prize in the game's history and the world's second largest lottery prize. Sutton sold a million dollar powerball ticket on Tuesday. (AP Photo/Nati Harnik)

Sheila Sutton sells Powerball tickets at the Super C convenience store in Lincoln, Neb., Friday, May 17, 2013. Powerball officials say the jackpot has climbed to an estimated $600 million, making it the largest prize in the game's history and the world's second largest lottery prize (AP Photo/Nati Harnik)

Randy Kirby of Lincoln buys a Powerball ticket at a Super C convenience store in Lincoln, Neb., Friday, May 17, 2013, where a million dollar powerball ticket was sold on Tuesday. Powerball officials say the jackpot has climbed to an estimated $600 million, making it the largest prize in the game's history and the world's second largest lottery prize. (AP Photo/Nati Harnik)

A customer holds his Powerball ticket at a Super C convenience store in Lincoln, Neb., Friday, May 17, 2013. Powerball officials say the jackpot has climbed to an estimated $600 million, making it the largest prize in the game's history and the world's second largest lottery prize. (AP Photo/Nati Harnik)

FILE - In this Feb. 22, 2006 file photo, the eight ConAgra plant workers hold up their ceremonial checks after winning the $365 million dollar Nebraska Powerball lottery at a news conference in Lincoln, Neb. Work pools for big jackpots are often fraught with controversy, resulting in lawsuits, broken friendships and worse: delayed payouts. (AP Photo/Nati Harnik/File)

(AP) ? In workplaces across the nation, Americans are inviting their colleagues to chip in $2 for a Powerball ticket and a shared daydream.

The office lottery pool is a way to improve your odds and have a little fun with co-workers. And besides, who wants to be the only person at work the next day when everyone quits?

With $600 million on the line, this is the time to play. It's the largest-ever Powerball jackpot and the second-largest world jackpot of all time. And it could get even bigger before Saturday's drawing.

The Multi-State Lottery Association recognizes the popularity of work pools, especially when the stakes are so high. In the last few years, lottery officials have offered tips for organizing pools.

"The appeal is they can stretch the value of their $2," said Norm Lingle, executive director of the South Dakota Lottery and chairman of the Powerball Executive Committee.

But it's important to be careful. Workplace pools that yield big jackpots sometimes result in lawsuits, broken friendships and delayed payouts. Follow these steps to make sure you're ready to divide your winnings.

___

KNOW THE RULES

Lottery officials encourage pools organizers to lay down rules, put them in writing and distribute the details to all participants before the winning numbers are drawn.

Linda Golden, of Gettysburg, Pa., may set the bar for how to manage an office lottery pool. An employee for more than three decades at a printing company called Quad Graphics, Golden has organized a pool for years and requires everyone to sign in, showing they contributed. She had 14 co-workers on board when the jackpot pushed past $200 million in late March.

They only won $4. But instead of distributing what would have amounted to about 27 cents a person, Golden bought more tickets for the $1 million Powerball drawing on March 27 without telling the others. She hit the jackpot and never gave a thought to keeping the winnings all for herself. One co-worker was a woman who used a walker because of a foot problem. Another had just been to the emergency room because of a knee problem.

"I say it over and over again. That ticket we won was meant for those two ladies and the rest of (the group) is there for the ride," she said.

After taxes, each person ended up with about $50,000.

Golden's winning ticket has only stirred more excitement in her office for Saturday's giant Powerball jackpot. She estimated she had 26 people in her pool this time.

"This time, it's starting to take up so much of my time. So many people wanted to join," she said. "It's kind of getting out of hand."

In Collinsville, Ill., just across the Mississippi River from St. Louis, seven firefighters were pooling their money for a $14 ticket that offered seven plays.

Mike Harris keeps the pool in order by distributing a photocopy of the ticket to each contributor and scrawling their names on the handout. To him, it's just common sense.

"There's no confusion," he said. "This is the ticket we have."

___

THE GOOD AND THE UGLY

If you're the person buying the tickets, make sure co-workers are aware if you plan to buy personal tickets on the side.

That didn't happen in Indianapolis, where a hairdresser became involved in a lawsuit with seven of her former co-workers.

Christina Shaw claims the winning ticket wasn't part of an office pool. The hairstylists say they had all verbally agreed to share any winnings from any tickets purchased at the same time as those for the pool.

"People don't realize that this is serious business," said New Jersey attorney Rubin Sinins. He represented five construction workers who claimed a colleague cheated them out of a share of a multimillion-dollar lottery jackpot. The man claimed he won the 2009 jackpot on a personal ticket ? not with a ticket he bought as part a lottery pool.

There's also an Ohio man who missed his weekly lottery pool because of an injury, then later sued his co-workers for a chance to share their winning $99 million jackpot.

"When you go in with people in an agreement that involves potentially millions of dollars, you're talking about a contract," Sinins said. If a ticket wins, "then issues can arise as to who's actually part of the pool, who's entitled to the money, what proofs there are to establish that."

___

PLANNING FOR THE NEARLY IMPOSSIBLE

It's smart to plan. But it also can feel silly to plan for something that is nearly impossible to win. Or is it?

The chances of winning the latest jackpot are about 1 in 175.2 million. That's how many ways a person can combine the numbers to make a play. But Sinins said it's still important to consider what would happen if you somehow overcame the odds.

"If there was no chance, you wouldn't do it," he said. "And you obviously want to do it. So you want to make sure that there's no problem afterward."

___

Associated Press writers Jim Suhr in Collinsville, Ill., and Genaro Armas in State College, Pa., contributed to this report.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-05-17-Powerball%20Jackpot-Work%20Pools/id-86a8891ba75a446eb269850cc8bf1519

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Porsche shows 918 Spyder in production form

Porsche shows 918 Spyder hybrid in final production form

Porsche isn't about to let the LaFerrari steal the hybrid spotlight: it just unveiled the finished design of the 918 Spyder, which is expected to ship as a 2015 model. The look won't shock anyone keeping up with their spy videos, although Porsche's formal unveiling helps firm up the specifications that customers will get if they've dutifully shelled out $845,000. The performance is even more intimidating than it was in 2011, we know that much: there's 887HP of combined V8 and plug-in electric power, a 0-62MPH time of 2.8 seconds and up to 18 miles of gas-free driving. About the only disappointment (price notwithstanding) is the lack of options beyond a weight reduction package. We doubt many Spyder buyers will complain when they can even outrace a 911 GT3.

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Friday, May 17, 2013

Emma Watson's 'Bling Ring' Inspiration: The Kardashians

Emma Watson has been internationally famous since she was nine years old. She has no idea what it's like to desperately crave fame and status, like her character in The Bling Ring. Fortunately, the former Harry Potter star had some excellent role models: the Kardashians!

Source: http://www.ivillage.com/emma-watsons-fame-hungry-inspiration-bling-ring-kardashians/1-a-536423?dst=iv%3AiVillage%3Aemma-watsons-fame-hungry-inspiration-bling-ring-kardashians-536423

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South Florida Insurance Fraud: Feds Charge 92 Over $20 Million In ...

The vehicle collisions looked like typical South Florida accidents with motorists and passengers reporting they needed treatment from chiropractors and massage therapists.

But investigators said the crashes were carefully staged by willing participants who were trained how to defraud the insurance system to make money for themselves and a highly organized group of medical professionals, clinic owners and recruiters.

Investigators announced charges Thursday against 33 people they said were involved in staging accidents for insurance fraud -- the latest hit in a three-year investigation that identified about $20 million in fraudulently obtained payouts from insurers.

"If you get upset about your car insurance premiums going up, this crime is one of the reasons why," said William J. Maddalena, the assistant special agent in charge of FBI Miami. "Every time an insurance payout is made for a staged accident in Florida, we all feel the pain in the pocketbook."

Operation Sledgehammer, a state and federal investigation, has led to charges being filed against a total of 92 defendants from Palm Beach, Broward and Miami-Dade counties. Those already convicted have been ordered to pay more than $5 million in restitution to insurance companies so far, prosecutors said.

The operation got its code name when undercover investigators saw suspects using a sledgehammer to make vehicles look like they'd been in an accident.

The fraud involved a "massive," complicated, highly organized scheme that investigators said included everyone from clinic owners and medical staff who provided fraudulent diagnoses and prescribed fake treatment, to office workers who billed for the services, and recruiters who found accident "victims" and trained them to stage collisions on the streets and highways of South Florida.

The criminal charges filed this week targeted 33 people from West Palm Beach, Lake Worth, Weston, Parkland, Davie, Hollywood, Boynton Beach, Greenacres, Doral, Miami and Hialeah with a slew of charges including mail fraud and money-laundering conspiracies, structuring financial transactions and participating in staged-accident fraud.

The scheme dated from about October 2006 to December 2012 and the defendants staged accidents and submitted false insurance claims through 21 chiropractic clinics in Palm Beach and Miami-Dade counties that they controlled, authorities said.

Of the 33 charged, 26 have been arrested or agreed to surrender, federal and state law enforcement officials said at a Thursday afternoon news conference in the U.S. Attorney's Office in West Palm Beach.

The ringleaders recruited chiropractors Lazaro Rodriguez, 58, of Doral, and Kenneth Karow, 53, of Boynton Beach, and others to serve as the named owners of some of the clinics, investigators said.

Five of the defendants, including alleged ringleaders Vladimir Lopez, 38, and Lazaro Vigoa Mauri, 45, both formerly of West Palm Beach, have fled to Cuba and they and the other defendants who have not yet been caught are considered fugitives, authorities said.

Maddalena said the investigation was kicked off by a tip from a member of the public and urged anyone with information to call their local police department.

The participants in the fraud were trained by recruiters on how to make the accidents look realistic, how to file police reports and insurance claims, how to fake injuries and where to go for treatment, Maddalena said. The ringleaders made sure that insurance checks were deposited into accounts they controlled so they could pay the participants, he said.

Of the 92 people charged to date in the fraud scheme, the U.S. Attorney's Office filed federal charges against 56 of them and the Palm Beach State Attorney's Office filed state charges against 36 of them.

Lawrence Schechtman, 45, a chiropractor from Parkland, Olinda Rodriguez, 39, a massage therapist from West Palm Beach, and Iris Roca, 41, a massage therapist from Davie, were charged separately with participating in staged accident fraud schemes and are expected to surrender in the next few days.

pmcmahon@tribune.com, 954-356-4533 or Twitter @SentinelPaula ___

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Source: http://www.huffingtonpost.com/2013/05/17/south-florida-insurance-fraud_n_3289964.html

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Engineers monitor heart health using paper-thin flexible 'skin'

May 16, 2013 ? Most of us don't ponder our pulses outside of the gym. But doctors use the human pulse as a diagnostic tool to monitor heart health.

Zhenan Bao, a professor of chemical engineering at Stanford, has developed a heart monitor thinner than a dollar bill and no wider than a postage stamp. The flexible skin-like monitor, worn under an adhesive bandage on the wrist, is sensitive enough to help doctors detect stiff arteries and cardiovascular problems.

The devices could one day be used to continuously track heart health and provide doctors a safer method of measuring a key vital sign for newborn and other high-risk surgery patients.

"The pulse is related to the condition of the artery and the condition of the heart," said Bao, whose lab develops artificial skin-like materials. "The better the sensor, the better doctors can catch problems before they develop."

Your pulse

To find your pulse, press your index and middle finger into the underside of your opposite wrist. You should feel the steady rhythm of your heart as it pumps blood through your veins.

Each beat you feel is actually made up of two distinct peaks, even though you can't tell them apart with just your fingers. The first, larger peak is from your heart pumping out blood. Shortly after a heartbeat, your lower body sends a reflecting wave back to your artery system, creating a smaller second peak.

The relative sizes of these two peaks can be used by medical experts to measure your heart's health.

"You can use the ratio of the two peaks to determine the stiffness of the artery, for example," said Gregor Schwartz, a post-doctoral fellow and a physicist for the project. "If there is a change in the heart's condition, the wave pattern will change. Fortunately, when I tested this on myself, my heart looked fine."

To make the heart monitor both sensitive and small, Bao's team uses a thin middle layer of rubber covered with tiny pyramid bumps. Each mold-made pyramid is only a few microns across -- smaller than a human red blood cell.

When pressure is put on the device, the pyramids deform slightly, changing the size of the gap between the two halves of the device. This change in separation causes a measurable change in the electromagnetic field and the current flow in the device.

The more pressure placed on the monitor, the more the pyramids deform and the larger the change in the electromagnetic field. Using many of these sensors on a prosthetic limb could act like an electronic skin, creating an artificial sense of touch.

When the sensor is placed on someone's wrist using an adhesive bandage, the sensor can measure that person's pulse wave as it reverberates through the body.

The device is so sensitive that it can detect more than just the two peaks of a pulse wave. When engineers looked at the wave drawn by their device, they noticed small bumps in the tail of the pulse wave invisible to conventional sensors. Bao said she believes these fluctuations could potentially be used for more detailed diagnostics in the future.

Blood pressure and babies

Doctors already use similar, albeit much bulkier, sensors to keep track of a patient's heart health during surgery or when taking a new medication. But in the future Bao's device could help keep track of another vital sign.

"In theory, this kind of sensor can be used to measure blood pressure," said Schwartz. "Once you have it calibrated, you can use the signal of your pulse to calculate your blood pressure."

This non-invasive method of monitoring heart health could replace devices inserted directly into an artery, called intravascular catheters. These catheters create a high risk of infection, making them impractical for newborns and high-risk patients. Thus, an external monitor like Bao's could provide doctors a safer way to gather information about the heart, especially during infant surgeries.

Bao's team is working with other Stanford researchers to make the device completely wireless. Using wireless communication, doctors could receive a patient's minute-by-minute heart status via cell phone, all thanks to a device as thick as a human hair.

"For some patients with a potential heart disease, wearing a bandage would allow them to constantly measure their heart's condition," Bao said. "This could be done without interfering with their daily life at all, since it really just requires wearing a small bandage."

The team published its work in the May 12 edition of Nature Communications. The team's research is supported by funding from the National Science Foundation and the Air Force Office of Scientific Research.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/matter_energy/technology/~3/-oiQkXr5dnA/130516105702.htm

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